Spectrum | Autism Research News

Going on Trial: Epidiolex for autism; arbaclofen tests; pain monitoring

Tue, 30 May 2023 12:50:00 +0200

This month’s issue of Going on Trial takes a sneak peek at some early null results from a small trial of a cannabidiol-based drug for autism, among other recent drug developments.

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Swings and misses with Jeremy Veenstra-VanderWeele

Tue, 30 May 2023 12:50:00 +0200

A careful clinician who prizes evidence, Jeremy Veenstra-VanderWeele is happy to embrace trial failures, as long as he learns from them.

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Community Newsletter: ‘Scammer participants’; dopamine receptor structures

Sun, 28 May 2023 12:50:00 +0200

A potential threat to the integrity of data collected online and an analysis of the structure and function of dopamine receptors caught researchers’ attention on social media this week.

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Spotted around the web: Brain connectivity; microglia; ketamine

Fri, 26 May 2023 12:50:43 +0200

Here is a roundup of news and research for the week of 22 May.

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Medicaid waivers curb disenrollment among autistic young adults

Fri, 26 May 2023 12:50:00 +0200

Autistic people tend to drop out of Medicaid once they reach adulthood in states that don’t waive the income restrictions on enrollment.

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Antihistamine aids myelination in Pitt-Hopkins mice

Thu, 25 May 2023 12:50:00 +0200

The drug clemastine and other compounds that fortify the protective sheath around neurons may prove therapeutic for some genetic neurodevelopmental conditions.

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Nerve regeneration paper retracted over faked data

Wed, 24 May 2023 12:50:00 +0200

The paper marks the second retraction for one of the co-authors.

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‘Polygenic risk scores’ for autism, explained

Tue, 23 May 2023 12:50:00 +0200

These scores — composite measures of a person’s autism-linked common genetic variants — cannot predict an autism diagnosis but could help researchers better understand the condition’s underlying biology.

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Neuroscience journal retracts 13 papers at once

Mon, 22 May 2023 12:50:00 +0200

The papers were flagged by a method that has now been called into question.

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Community Newsletter: 3D motion tool; Imaging Neuroscience announcement

Sun, 21 May 2023 12:50:00 +0200

This week on social media, scientists discussed a new tool to quantify motion in 3D and responded to the announcement of the launch of Imaging Neuroscience.

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Spotted around the web: Necroptosis genes; antisense oligos; racial disparities

Fri, 19 May 2023 12:50:18 +0200

Here is a roundup of news and research for the week of 15 May.

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Ruth Carper: Imaging the aging brain in autistic adults

Fri, 19 May 2023 12:50:12 +0200

Few studies have tracked how brain structure and function change across adulthood in people with autism. Carper and her colleagues are collecting data to fill this gap.

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Genetic background sways effects of autism-linked mutation

Thu, 18 May 2023 12:50:00 +0200

Experiments offer clues to why certain mutations are associated with autism in some people and not others.

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Null and Noteworthy: Arbaclofen results; another oxytocin edition

Wed, 17 May 2023 12:50:00 +0200

New data from clinical trials of arbaclofen and oxytocin underscore the murkiness of null results. Plus, researchers seek clarity on the neurodevelopmental effects of oxytocin during childbirth.

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Autism intervention before age 2 may aid social, language skills

Tue, 16 May 2023 12:50:00 +0200

Autistic toddlers who receive a personalized intervention at about 18 months of age gain more abilities than those who start the therapy nine months later.

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Dataset maps connectivity in 40,000 brains

Mon, 15 May 2023 12:50:00 +0200

The new resource aims to aid reproducibility in imaging research.

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Community Newsletter: Social memory; viral vector for striatum; brain gene expression

Sun, 14 May 2023 12:50:00 +0200

Several studies caught researchers’ attention on social media this week, including one that compared gene expression in living versus postmortem samples of the human brain.

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Spotted around the web: INSAR; cerebellar gene expression; pangenome

Fri, 12 May 2023 12:50:39 +0200

Here is a roundup of news and research for the week of 8 May.

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Autism-related genes converge on microglia and dopamine in zebrafish

Fri, 12 May 2023 12:50:00 +0200

The findings add to the growing evidence that genes with disparate functions can play similar roles in brain development.

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Grafted organoids reveal how microglia adapt to shifting brain environments

Thu, 11 May 2023 17:00:00 +0200

The chimeric mouse model could provide a more realistic way to study microglia’s roles in brain conditions such as autism.

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