Early-career researchers talk about the challenges around taking time off, and a new study shows that young scientists tend to be more innovative than their older colleagues.

The post <em>Spectrum</em> Launch: Carving out vacation time as an early-career researcher appeared first on Spectrum | Autism Research News.

The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.

The post Multi-omics study captures CNTNAP2’s far-ranging effects appeared first on Spectrum | Autism Research News.

A new method that merges tissue expansion, light-sheet microscopy and automated image segmentation can reconstruct neural circuits in about a week.

The post Microscopy mash-up quantifies, maps neural circuits appeared first on Spectrum | Autism Research News.

High rates of autism are linked to lower socioeconomic status and minority ethnic groups, according to the largest-ever autism incidence study.

The post Autism incidence in England varies by ethnicity, class, location appeared first on Spectrum | Autism Research News.

Faulty mTOR signaling, implicated in syndromic forms of autism, also hinders cells grown from people with idiopathic autism or autism-linked deletions on chromosome 16.

The post Autism subgroups converge on cell growth pathway appeared first on Spectrum | Autism Research News.

Three threads on autism-related research snared the attention of neuroscientists on Twitter this week.

The post Community Newsletter: Sex bias; synapse formation; gene convergence appeared first on Spectrum | Autism Research News.

Here is a roundup of news and research for the week of 28 November.

The post Spotted around the web: Protein ubiquitination; meninges immunity; scientific image problems appeared first on Spectrum | Autism Research News.

The method yields complex organoids that more closely mimic embryonic brain development than do those cultured in other ways.

The post One-rosette technique grows well-organized organoids appeared first on Spectrum | Autism Research News.

Within the 16p region of the genome, the two types of variants similarly decrease neuronal gene expression — an effect that may reflect their spatial relationship.

The post Common and rare autism-linked variants share functional effects appeared first on Spectrum | Autism Research News.

The model enables the study of autism-linked genes at the earliest stages of neural development.

The post ‘Assembloids’ lay bare autism-linked genes that hamper neuron development appeared first on Spectrum | Autism Research News.

A young researcher faces down the skeptics.

The post How Helen Willsey broke new ground, frogs in hand appeared first on Spectrum | Autism Research News.

Psychiatric genomics promises to shed light on the genetic basis of autism, but it’s vital to include Africa in this research, Iyegbe and Okewole say.

The post Africa’s genomic role: Q&A with Conrad Iyegbe and Niran Okewole appeared first on Spectrum | Autism Research News.

Here is a roundup of news and research for the weeks of 14 and 21 November.

The post Spotted around the web: Neuroscience 2022; brain condensates; university strikes appeared first on Spectrum | Autism Research News.

The signal, called CD47, is disrupted in autistic people who have a larger-than-average head.

The post Excess of ‘don’t eat me’ cell signals may drive brain enlargement in autism appeared first on Spectrum | Autism Research News.

The function of microglia and astrocytes in the brain may mediate the intersection of sex-differential biology and autism biology.

The post Autism’s sex bias tied to glial, immune cell gene expression appeared first on Spectrum | Autism Research News.

Using imaging methods to sort mouse models of autism may help identify subtypes of autistic people with similar underlying biology.

The post Shared brain structure, connectivity hint at autism subgroups appeared first on Spectrum | Autism Research News.

Brain cell clusters serve as drug screens and reveal connectivity differences for autism-linked conditions, two new models show.

The post Organoids identify potential therapies, circuit flaws for autism-linked syndromes appeared first on Spectrum | Autism Research News.

This week we’re highlighting the Twitter chatter from the Society for Neuroscience’s annual meeting, held in San Diego, California, last week.

The post Community Newsletter: Highlights from Neuroscience 2022 appeared first on Spectrum | Autism Research News.

UBE3A, a key gene associated with both autism-linked conditions, can explain most — but not all — of the syndromes’ atypical neuronal properties.

The post Single gene insufficient to account for dup15q, Angelman traits appeared first on Spectrum | Autism Research News.

Pagani used mouse models to connect autism etiologies to brain connectivity alterations and then found similar alterations in people with idiopathic forms of the condition.

The post Subtyping autism using fMRI: A quick take at SfN with Marco Pagani appeared first on Spectrum | Autism Research News.