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What's Your Problem?

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The fish we eat usually die slowly, suffocating after they’re pulled out of the water. Saif Khawaja is the co-founder and CEO of a company called Shinkei. Saif's problem is this: Can he build a machine to efficiently kill fish in a way that is more humane?

In this episode, Saif explains:

How he came to believe that our current fishing practices are inhumane How ...

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Catherine Nakalembe is an assistant professor at the University of Maryland and the head of the Africa program at NASA Harvest, which uses satellite images to track agriculture around the world. Catherine’s problem is this: How do you predict when a famine is coming – and how do you convince leaders to act in time?

In this episode, Catherine explains:

How satelli...

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When Dr. Lara Jehi began treating epilepsy patients in the 2000s, critical surgical decisions were driven more by clinician intuition and expertise than data. Today, she is a leader of IBM and Cleveland Clinic’s Discovery Accelerator, using advanced AI and quantum computing to transform how researchers analyze data, simulate molecules, accelerate drug discovery, and develop m...


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Nir Barzilai is a physician and a researcher at the Albert Einstein College of Medicine in New York, where he runs the Institute for Geroscience. Nir’s problem is this: How can we use lifestyle changes and drugs to slow the process of aging?

In this episode, Nir explains:

The search for biological markers of aging The existing drugs that might reduce the risk of ...

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