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Background: Severe complications following complex penile reconstructive surgery are uncommon but may be devastating, particularly when synthetic grafts are employed. Infection and progressive penile skin necrosis can rapidly compromise erectile structures and functional outcomes. Evidence guiding the optimal management of extensive necrosis after graft-based...
Background and Objective: Metabolic alterations in chronic diseases such as dyslipidemia, type 2 diabetes mellitus (T2DM), and obesity disrupt hormonal regulation and perpetuate inflammation and oxidative stress across multiple systems, including the reproductive system. Focusing on the physiological functions of glucagon-like peptide-1 (GLP-1) and the organ-...
Background: There are numerous published societal guidelines for the management of men with erectile dysfunction (ED), often with specific nuances and some variations in diagnostic and treatment strategies based on relevant locoregional factors such as sociocultural barriers and differences in emphasis between urological organisations versus sexual medicine s...