This Week in Virology

TWiV explains results of a dengue virus human challenge which reveals that preexisting immunity shapes viral replication and broadly protective responses, and how influenza virus antagonizes self-sensing by RIG-I to enhance viral replication.

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are cautiously elated by results of election day 2026 on the backdrop of additional measles associated deaths in Wisconsin, Pennsylvania and New York, return of mpox, Chagas disease in Texas, hippopotami dying from anthrax infections, increase in dengue cases in Florida before Dr. Griffin deep dives into rec...

TWiV discusses an outbreak of H5N1 influenza viruses in Utah farmed mink, and divergent species-specific antiviral responses in Marburg virus infected cells from reservoir bats and humans.

In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by the continued upheaval of leadership at the CDC, recent news of H5 highly pathogenic influenza virus found on mink farms in Utah and in the polar bear population of Greenland, continuing spread of dengue virus in Florida and screwworm in the US, the Ebola outbreak in Kenya, identification o...

TWiV explains projected effects of removing school-entry vaccination requirements on measles transmission in Florida and evidence that HLA class I escape drives the evolution of SARS-CoV-2 in human populations.