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Dr. Giulia Enders has changed the way millions of people think about the human body.

As a physician, microbiome researcher, and bestselling author, she has spent years studying the surprising role the gut plays in everything from digestion and immunity to mood, sleep, metabolism, and long-term health.

In this conversation, Giulia explains how your gut shape...


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Bill Gurley spent years on Wall Street, built his career as a partner at Benchmark, worked through Uber’s hypergrowth era, and now serves on the board of the Santa Fe Institute, where he studies complexity and systems thinking.

In this episode, Bill shares the mental models he returns to most, including systems thinking, second- and third-order effects, and the importa...


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Mark Pincus is the creator behind Farmville and Words with Friends. He built Zynga into one of the biggest gaming companies in the world and helped shape the early era of social products on the internet.

In this conversation, he breaks down how great founders spot winning ideas early, why most startups build the wrong thing, and how products become part of people’s dai...


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