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Mount Sinai Med-Lit Review

Clinical Question: In patients with chronic coronary syndrome and high atherothrombotic risk on long-term oral anticoagulation, does the addition of aspirin improve outcomes?

Background: The ideal antithrombotic regimen for patients with chronic coronary syndrome at high atherothrombot...


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Mount Sinai Med-Lit Review

Clinical question: What is the optimal duration of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) with drug-eluting stent (DES) placement in patients according to bleeding risk (high bleeding risk versus non-high bleeding risk)?

Background: Previous stu...


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Mount Sinai Med-Lit Review

Clinical question: Does actively increasing serum potassium to the high-normal range (4.5 to 5.0 mmol/L) reduce malignant ventricular arrhythmias, arrhythmia-related hospitalizations, or death in patients with an implantable cardioverter-defibrillator (ICD) and baseline potassium of 4.3 mmol/L or less?


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Mount Sinai Med-Lit Review

Clinical question: Do acetylcholinesterase inhibitors help reduce the occurrence and severity of delirium in hospitalized patients?

Background: Delirium is a frequent complication in hospitalized patients and is associated with significant morbidity and mortality. Acetylcholinesterase ...


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Mount Sinai Med-Lit Review

Clinical question: Are beta-blockers beneficial in patients discharged after receiving invasive care for a myocardial infarction (MI) and with preserved left ventricular ejection fraction (ejection fraction greater than 40%)?

Background: Current guidelines recommend discharging all pat...


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