Dabcyl was one of the first true dark quenchers used in oligos, popularised by its use in the original Molecular Beacons. In this ‘Know Your Oligo Mod’ blog, we’ll cover Dabcyl’s strengths and weaknesses, its uses in qPCR and other app...

Delivering better cultivars, faster, is a continuous challenge for plant breeders. Genetic tools and discoveries have transformed breeding strategies, but even once suitable trait-markers are identified, turning these...

The scope and demand for nucleic acid therapeutics is growing rapidl...

Phosphate groups are one of the most popular modifications for our custom oligos. In this Know Your Oligo Mod blog post, we’ll explore how adding phosphates to either end of the oligonucleotide can dramatically alter its beh...