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Nucleic Acid Therapeutics Toolbox: Givosiran, the first liver-targeted siRNA drug

The success of small interfering RNAs (siRNAs) therapeutics in treating rare genetic liver disorders has spurred significant investment to expand these drugs to more common conditions, from hypertension to hepatitis B.

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Know Your Oligo Mod – Biotin

Biotin is a very commonly used label for oligonucleotides, thanks to its high affinity for streptavidin. This property makes it ideal for a wide range of experiments, and in this ‘Know Your Oligo Mod’ blog post we’ll explore some of the options availa...

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Unlocking the potential for circular RNA in molecular diagnostics
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Set up and walk away: same day targeted genotyping
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Nucleic Acid Therapeutics Toolbox: Mipomersen, the first gapmer
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