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Infant cholestasis is conjugated hyperbilirubinemia (often with dark urine and acholic stools) and demands a differential that includes common genetic/metabolic liver disease such as alpha-1 antitrypsin deficiency....


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After a Whipple procedure, persistent weight loss with low fat-soluble vitamins despite “enzymes” usually means PERT isn’t being delivered effectively—optimize formulation and add acid suppression. 


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In a tiered BLS/ALS EMS system, severe femur-fracture pain that prevents splinting should trigger ALS/paramedic response for analgesia, not forced restraint or transport without immobilization. 


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When patients require NSAIDs, calcium channel blockers are the antihypertensive class whose BP-lowering effect is least blunted.


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