Science

In the emerging landscape of drug discovery, Chinese herbal medicines (CHMs) have long represented both a rich resource and a complex challenge. Despite their historical importance in traditional Chinese medicine (TCM) and their contribution to groundbreaking drugs like artemisinin and ephedrine, CHMs have struggled to fully integrate into modern pharmaceutical pipelines. Onl...

Advances in cellular immunotherapy have revolutionized cancer treatment, yet significant challenges such as high costs and limited antigen specificity persist, particularly in combating B lymphoma. A newly published study in the journal Engineering addresses these hurdles by elucidating cutting-edge techniques for live-cell glycocalyx engineering, offering a transfor...

A groundbreaking study published in the journal Engineering has unveiled a crucial role for fucosylated immunoglobulin G (IgG) in driving adipose tissue dysfunction during aging. This discovery sheds new light on the molecular underpinnings of metabolic decline with age and suggests that targeting IgG fucosylation could pave the way for innovative therapies aimed at ...

As populations around the world age rapidly, healthcare providers and researchers alike grapple with the complex challenges posed by the needs of older adults. One of the most pressing concerns in geriatric medicine is the risk of falling, particularly after hip surgery—a common intervention for injuries such as fractures or degenerative diseases. The consequences of falls in...

In a groundbreaking development at the forefront of molecular magnetism, researchers have synthesized a novel three-dimensional molecular framework, Cr(pyrazine)₃, that exhibits an extraordinary form of magnetism rarely observed in molecular systems. This framework adopts a cubic ReO₃-type structure, a characteristic topology renowned for its structural flexibility but seldom...