Russian Journal of Infection and Immunity

Unlike most other mammals, humans have lost the ability to express alpha-1.3-galactosyltransferase (α1.3GT) due to mutations in the GGTA1 gene thereby underlying inability of human cells to synthesize Gala1–3Galb1–4GlcNAc-terminated glycans (αGal), also present in bacterial and viral glycopolymers. The latter are not only highly immunogenic to humans, but also cause ...

The Ob-Irtyshsky focus, which includes the Tyumen region is largest among Opisthorchis felineus invasion sites. The high intensity of invasion spreading in the outbreak underlies a high risk of infection often occurring with acute stage for the residents of the Tyumen region. The aim of this study was to evaluate the immunological parameters in patients with acute op...

Background. Parenteral hepatitis B (HBV), C (HCV), and D (HDV) virus infections pose a global public health problem. It is critical to conduct epidemiological study for planning effective preventive and therapeutic interventions in the Kherson Region during post-crisis healthcare restoration. The study was aimed to comprehensively assess prevalence of population pare...

Viral hepatitis holds a leading place among infectious diseases. The morbidity rate of chronic hepatitis C (HСV) among children in the Russian Federation is 1.29 per 100 000 population. Increasing access to antiviral therapy in childhood contributes to achieving the global health goal on HСV elimination. The aim of the study was to summarize the epidemiological characteristic...

Seroepidemiological studies are essential for epidemiological surveillance of vaccine-preventable airborne infections prevented in children through using combination vaccines. The aim of the study was to assess post-vaccination immunity to diphtheria, pertussis, measles, rubella and mumps in children and adolescents living in the Republic of Karelia. Materials and methods...