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Website title: Microscopes and Imaging Systems | Leica Microsystems

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Overview of Fluorescent Dyes in terms of Applications and Properties

An introduction to commonly used fluorescent dyes and an overview of their characteristics are given in this article. Fluorescence microscopy is used for the study of specific cellular components with the help of fluorescent dyes, fluorescent proteins, or immunofluorescent stains using antibodies. Thanks to a large variety of fluorescent agents, fluorescence microscopy can be...


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History, Developments and Trends of Microscopy in Cancer Research

Cancer is a global disease, with 18 million new cases diagnosed and 10 million cancer-related deaths worldwide in 2020. This burden is set to increase, with a projected increase in cases of ~55% by 2040. Research into understanding cancer initiation, development and to develop

new diagnostic tools and therapeutic approaches is vital.


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Eliminating Electrostatic Interference in Laser Microdissection

Electrostatic charge in laser microdissection (LMD) causes two critical failures: samples stick to charged surfaces and are lost, or samples fly into adjacent wells and cause cross-contamination. We integrated a bartype ionizer into the Leica LMD7 environmental chamber. The ionizer reduced electrostatic displacement from 16% (16/100 cuts) to 0.2% (1/450+ cuts). Collection int...


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Researchers Insights: Microscopy in Cancer Research

Discover how imaging techniques are driving cancer research forward. In this issue, we present comprehensive multimodal studies using microscopy, as well as new directions in intraoperative cancer imaging, diagnosis and treatment solutions.


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Predictive Service Prevents Downtime in Ghent

At the VIB BioImaging Core in Ghent, Belgium, researchers depend on Leica’s Stellaris 8 confocal microscope to explore the frontiers of biomedical science. When Leica’s RemoteCare system detected a critically low coolant level in the instrument’s chiller, the service team reacted immediately — preventing potential overheating and keeping the microscope fully operational.


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