Research, Society and Development

Background: Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Immune evasion and chronic inflammation are central determinants of tumor progression and therapeutic resistance. We aimed to analyze recent scientific literature addressing the role of myeloid-derived suppressor cells (MDSCs) in lung cancer, focusing on their mechanisms of action...

Objective: to propose a neuropsychiatric hypothesis in which Korsakoff syndrome is not restricted to an amnestic disorder but involves a disruption of the integration of present experience, affective valuation, and autobiographical narrative. Methodology: a narrative and integrative review was conducted, combining classical European psychiatric descriptions with recent neurob...

In contact sports, mats play an important role in protecting athletes against impacts; however, they represent an invisible health hazard due to the high risk of contamination by pathogens, favored by intense friction and skin-to-skin contact, conditions that contribute to infections of varying degrees of severity. In this context, this study aims to discuss the contamination...

Objective: To understand the manifestations and specificities of the grieving process in individuals who have experienced the loss of a pet. Methodology: This is a descriptive, qualitative study conducted with 21 dog and cat owners. Data collection took place between January and March 2025 via semi-structured interviews that were recorded and transcribed verbatim. The textual...

Myeloid-derived suppressor cells (MDSCs) play an important role in colorectal cancer progression by contributing to the evasion of the antitumor immune response, treatment resistance, and metastasis formation. This integrative review aimed to analyze the mechanisms by which MDSCs promote the suppression of the antitumor immune response in colorectal cancer, as well as their c...