Research, Society and Development

Objective: To describe the epidemiological profile of live births with Down Syndrome (DS) and their mothers in the state of Pernambuco, Brazil, from 2010 to 2023. Methodology: A quantitative, cross-sectional, and descriptive study was conducted using secondary data from the Live Birth Information System (SINASC), available in the DATASUS database. Maternal, gestational, and n...

The freehand technique depends on the operator's experience and may result in deviations in implant positioning. Computed tomography combined with three-dimensional virtual planning increases predictability, even without surgical guides, although few studies have evaluated its accuracy in this context. This case study evaluated the accuracy of preoperative virtual planning in...

Ensiling tropical grasses is often constrained by low concentrations of soluble carbohydrates, high buffering capacity, and elevated moisture content, factors that impair lactic fermentation and reduce silage quality. The aim was to evaluate the effects of molasses inclusion on the fermentation characteristics, moisture content, and fiber composition of elephant grass (Pe...

Migraine is a highly prevalent chronic neurological disorder and one of the leading causes of disability worldwide. Among recent therapeutic advances, zavegepant stands out as the first calcitonin gene-related peptide (CGRP) receptor antagonist developed for intranasal administration and approved for the acute treatment of migraine in adults. This study aimed to evaluate the ...

Metabolic dysfunction-associated steatotic liver disease (MASLD) is one of the leading causes of chronic liver disease worldwide and is strongly associated with obesity and type 2 diabetes mellitus. Among emerging therapeutic strategies, tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, has shown promi...