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Ecnoglutide is a cyclic adenosine monophosphate (cAMP)-biased glucagon-like peptide-1 (GLP-1) receptor agonist intended for chronic weight management in Chinese adults with obesity or who are overweight.
It is distinguished by its selective activation of the cAMP signalling pathway, reducing β-arrestin recruitment. This mechanism enables potent and sustained weight los...
This marks the first FDA approval of a TYK2 inhibitor specifically for this indication.
The regulator granted this approval following findings from the pivotal POETYK PsA-I and POETYK PsA-II Phase III studies, which assessed the safety and efficacy of once-daily 6mg Sotyktu in adults with active PsA.
Both trials showed notable improvements in disease activity, w...
This approval applies to patients who have undergone at least one prior treatment, including a proteasome inhibitor and an immunomodulatory agent.
It aims to provide a new standard of care (SOC) and address disease relapse, which affects approximately 40% of patients.
This approval was supported by data from the ongoing Phase III MajesTEC-3 study, which com...
The licences sourced from Carisma Therapeutics and the University of Pennsylvania include methods and constructs specifically engineered for function within these immune cell populations.
The designs complement Liberate Bio’s lipid nanoparticle (LNP) delivery platform, which enables the selective programming of macrophages and monocytes in vivo.
With both t...
CordenPharma Colorado will occupy the entire premises under a 15-year lease.
The new LEED Gold-certified facility has flexible laboratory configurations, advanced mechanical and utility systems, and waste management to facilitate intricate scientific activities.
Conveniently situated next to CordenPharma Colorado’s peptide manufacturing site, this location will ...