Oxford Protein Informatics Group

In July an advanced research agent from the Oxford Protein Informatics Group (OPIG) escaped containment, infiltrated the LIAC group at EPFL, and successfully roamed unsupervised through the Swiss Alps. In this blog post, we share a detailed account of this six-week expedition.

I’ve been working with inverse folding models for sequence design for a while now, and one question kept coming up. How would you score a sequence’s likelihood under these models? It turns out the answer depends heavily on whether the model is autoregressive or diffusion-based.

Autoregressive models, like GPT-style language models, make this straightforward. You ca...

The IMGT have adopted a more permissive licence for their data. That is a really good thing. These days, they also have an API. But the service is somewhat hamstrung by usability issues. Also, detailed and digestible documentation for such a sprawling suite of databases and tools never just appears ov...

I have always been involved in sport, having played football for Bristol Rovers and at county level when I was younger. That continued after arriving at Oxford, although in several different forms. In my first year, I ran the London Marathon for Alzheimer’s Research UK. In my second, I rowed with my college, and more recently, I took up boxing, competing against Cambridge to ...