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Four people, three of them children, were killed Thursday in a shooting at an elementary school in Bend, Oregon. At least two people were hospitalized; their conditions were not released, the AP reports. "This is the kind of thing we never want to see happen in Bend," police spokesperson Sheila...

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Eric Deters, the Republican donor whose accusation that Kimberly Guilfoyle solicited $100,000 from him lead to her resignation as US ambassador to Greece, has sued her and her lawyers for defamation and threatened revelations that he said "might bring down the entire Trump administration." The suit, filed in Kentucky...

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Drugmakers are betting big that a new way of trashing bad proteins inside cells could reshape treatment for cancer and other diseases. The "protein degrader" drugs don't just block troublesome proteins, the Wall Street Journal reports; they tag them for destruction using the cell's own waste-disposal system, potentially reaching targets...

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Boardroom optimism just slipped into the red. A Conference Board survey of 131 Fortune 500 chiefs finds CEO confidence in the US economy dropping to 46 from 52 last quarter, reports Axios , which notes that a reading below 50 reflects negative sentiment. The new figure now roughly mirrors consumer gloom...

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Kimberly Guilfoyle's ouster as US ambassador to Greece highlights a pattern in President Trump's administration: women facing accusations of wrongdoing are regularly forced out, while scandal-ridden men sit tight, the New York Times reports. Guilfoyle is accused of asking a donor to pay off her $100,000 credit card bill....

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