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Neuroscientifically Challenged

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Neuroscientifically Challenged: Neuroscientifically Challenged

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In this video, I explore the brain mechanisms underlying rewarding experiences and addiction. I discuss dopamine’s role in reward and addictive behavior, the major dopamine pathways (mesolimbic, mesocortical, and nigrostriatal), and a range of addiction-related brain changes, including hypofrontality, heightened sensitivity to drug cues, blunted dopamine signaling, tolerance, an...

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In this video, I discuss the anatomy and physiology of the basal ganglia—a group of structures that play a key role in movement as well as a variety of non-motor functions. I cover the direct and indirect pathways, additional circuitry involved in non-motor functions, and several basal ganglia disorders, including Parkinson’s disease, Huntington’s disease, obsessive-compulsive d...

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