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Endocannabinoid Biology in Health & Disease | Nephi Stella | Episode 305

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The biology of endogenous cannabinoids & history of cannabinoid-based therapeutics

TOPICS DISCUSSED:

Anandamide vs 2-AG: The two major endocannabinoids with a shared arachidonic acid backbone but distinct head groups biolo...

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Mitochondria Peptides: MOTS-c, Humanin, Genetic Variation in Health & Disease | Pinchas Cohen | Episode 304

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Mitochondrial peptides act as stress signals that regulate metabolism, muscle mass, and neurodegeneration.

TOPICS DISCUSSED:

Mitochondria as Communication Hubs: Beyond ATP production, mitochondria encode peptides that regulate...

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Neuro-Immune Interactions: Pain, Inflammation, Peptides & Healing | Isaac Chiu | Episode 303

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How the nervous and immune systems communicate, using peptides and other signals, to regulate pain, itch, and inflammation.

TOPICS DISCUSSED:

Nociception & Pathogens: Sensory neurons detect bacterial toxins within seconds,...

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MOTS-c & Mitochondrial Peptides in Health & Aging | David Lee | Episode 302

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Mitochondrial peptide MOTS-c is a stress-induced signal that reprograms cell metabolism.

TOPICS DISCUSSED:

Mitochondrial Roles: Not just ATP production, but “speaker of the house” via communication molecules that “talk” to the...

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Peptides & GHK-Copper in Skin Health | Rahi Sarbaziha | Episode 301

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GHK-Copper and peptides in skin care, aging, and general health.

TOPICS DISCUSSED:

Endogenous Decline: GHK-copper levels peak in young adulthood then fall with age, reducing natural support for skin repair and collagen mainten...

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