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Title of MGH Center for Women's Mental Health: "Welcome to the MGH Center for Women’s Mental Health - MGH Center for Women's Mental Health"

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For women who require treatment with quetiapine during pregnancy, the available reproductive safety data are generally reassuring. The largest body of evidence does not suggest a meaningful increase in major congenital malformations, while metabolic effects, particularly gestational diabetes, remain an important consideration.

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Suicide risk during pregnancy and the postpartum, use of modafinil in pregnancy, and new treatment for menopausal symptoms are featured in this week’s roundup.

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A new study examines pregnancy outcomes among women using stimulants or atomoxetine during pregnancy, finding modest increases in some complications with stimulant use while highlighting important limitations of observational data.

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A large claims-based study found no increased risk for most outcomes with first-trimester stimulant exposure during pregnancy, but higher risks when use continued later in pregnancy.

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Estrogen-containing menopausal hormone therapy (MHT) may lower blood levels of lamotrigine, potentially reducing its effectiveness in some women with bipolar disorder. What do we know about this interaction, and does the risk differ with oral, transdermal, or vaginal estrogen?

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