Lifespan.io

Researchers have found that bound pieces of RNA and DNA in the cytoplasm of senescent cells encourage these cells to secrete inflammatory factors.

When transcription gets sticky

As part of the tran...

Scientists have targeted the thin fat layer around blood vessels with a transcription inhibitor, reducing symptoms of cardiometabolic disease [1].

When vessels can’t “just relax”

Cardiometabolic disease (CM...

In Aging Cell, researchers have described the way that antioxidants work against senescence in muscle cells by altering mTOR signaling.

Senescent cells don’t sense nutrients properly

In a new study, muscle-targeted viral-vector-based delivery of the protein FGF21 significantly increased median lifespan in male mice and improved many healthspan markers [1].

Control your e...

A team of reviewers has taken a look at the relationship between cancer, cellular senescence, and vascular overgrowth and published this information in Aging Cell.

Different gut cancers form through different pathways ...