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The Impact of Intraoperative Fibrinogen Replacement Therapy on the Clinical Outcome of Surgical Therapy for Type A A...

Acute type A aortic dissection (ATAAD) represents one of the most critical emergencies in cardiovascular surgery. Rapid diagnosis and surgical intervention are essential to prevent catastrophic complications such as rupture, cardiac tamponade, and organ malperfusion. However, ATAAD surgery is frequently complicated by severe perioperative coagulopathy. Hypothermia, cardiopulm...


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A Prospective Observational Study on Role of Intraoperative Renal & Muscle Oxygen Saturation on Post-Operative Serum...

Acute kidney injury (AKI) is one of the most common and clinically significant complications following cardiac surgery performed with cardiopulmonary bypass (CPB). Even small increases in serum creatinine after cardiac surgery have been associated with increased morbidity, mortality, and healthcare costs. Early identification of renal hypoperfusion during surgery could allow ...


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Mini-Compendium on Goal-Directed Perfusion (GDP): Integrating Hemodynamic and Metabolic Determinants of Oxygen Deliv...

Goal-Directed Perfusion (GDP) represents an evolving paradigm in cardiopulmonary bypass (CPB) management, emphasizing individualized physiological control of oxygen delivery, metabolic demand, and perfusion pressure during cardiac surgery. The article “Mini-Compendium on Goal-Directed Perfusion (GDP) Based on a Narrative Review” synthesizes current physiological principles an...


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Evaluating the Impact of a Standardized Protocol for Managing Refractory Vasoplegia After Cardiopulmonary Bypass

Refractory vasoplegia remains a challenging complication following cardiopulmonary bypass (CPB), characterized by profound vasodilation, high vasopressor requirements, and hemodynamic instability despite adequate cardiac output. In this 2026 study published in the Journal of Cardiothoracic and Vascular Anesthesia, Teletnick et al. evaluated the impact of implementing a standa...


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The Impact of Cardiopulmonary Bypass on the Structure and Mechanics of Red Blood Cells: Pilot Study

Cardiopulmonary bypass (CPB) is essential for modern cardiac surgery, enabling complex procedures on the heart and major vessels. However, exposure of blood to artificial surfaces, mechanical shear stress, hypothermia, and hemodilution can negatively affect red blood cells (RBCs). In this 2026 pilot study published in the Journal of Clinical Medicine, Sergunova et al. investi...


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