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Introduction to Computational Biology

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Message History

Acid-base balance and buffer systems [4 mins]
Acid-base balance and physiological pH - Buffer systems and bicarbonate - Respiratory acid-base regulation - Renal pH regulation mechanisms - Clinical acid-base disturbances - Homeostasis and physiological challenges

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AI-based regulatory compliance in drug development [38 mins]
Artificial intelligence (AI) - Regulatory frameworks - Data heterogeneity - Ethical and transparency concerns - Data-driven decision making - Algorithmic transparency and interpretability - Regulatory innovation and technological integration

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Virtual screening: personal reflections and future directions [45 mins]
Virtual Screening - Structure-based vs. ligand-based - Virtual screening case studies - Cryo-electron microscopy - AI: docking and scoring

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Clinical biochemistry: introduction [43 mins]
History of medicine - Modern medicine - Laboratory innovation - Measurement in laboratories - Precision and accuracy in laboratory measurements - Standardization and harmonization in laboratory measurements - Classification of laboratory measurements: Direct measurements - Biological variation - Total testing process - Laboratory medicine

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Liquid biopsy [29 mins]
Targets of liquid biopsy - Benefits of liquid biopsy - Circulating tumor DNA -Circulating Tumor Cells (CTCs) - Process of CTC detection - Advances in cancer detection - FDA status of liquid biopsy based methods for cancer detection

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