Inside Precision Medicine

Scientists have identified a promising therapeutic target that could disrupt the protective layer of sugar-derived molecules cancer cells use to evade the immune system. Results published today in Science Advances show that, under conditions of hyperglycemia, the HSF1 pro...

FLT3 inhibitors have changed the treatment landscape for FLT3-mutant acute myeloid leukemia, but they have not solved the central problem of relapse. Responses to drugs such as gilteritinib can be clinically meaningful, yet resistance frequently emerges, leaving researchers looking for the survival programs that AML cells use to escape targeted ...

The FDA has approved Moderna’s influenza vaccine, mFlusiva, for use in adults aged 50 years and older after positive Phase III results in a trial of more than 40,000 people in this age group.

This makes Moderna the first company to get an

Treatment with GLP-1 drugs is well established to have a positive effect on patients with type 2 diabetes and overweight. Many patients with these conditions also present with cardiovascular disease symptoms. While GLP-1 drug treatment has shown improvements, there is little evidence directly comparing the impacts of these drugs, including tirzepatide (marketed as Mounjaro) w...

Scientists have identified a compound with the potential to prevent the pathological changes that drive osteoarthritis and halt disease progression. In a study published today in ACS Omega, the researchers combined genomic analyses with AI-driven high-throughput screeni...