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Summary: Many people today feel that life in New York has become uniquely difficult. Some imagine that the city was cleaner, safer, and more livable in the distant past. Historical reality tells a different story: Preindustrial New York was marked by extreme filth, unsafe water, rampant disease, pervasive pove...


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“Since 2000, sub‑Saharan Africa has more than doubled primary enrolment and more than tripled secondary enrolment; in low‑income countries, secondary enrolment has almost quadrupled. Over the same period, the school‑age population fell by 9% in upper‑middle‑ and high‑income countries, rose by 25% in lower‑middle‑income countries and doubled in low‑income countries…

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“Since their peak less than three years ago, opioid overdose deaths dropped nearly by half as of October, according to a Stateline analysis. The drop comes as a shrinking fentanyl supply has made the drug weaker and less deadly and volunteer efforts get more people into treatment.

The weaker fentanyl tracks to a crackdown on materials used to make fentanyl in China ...


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“The growth of health care spending in the United States seems to have permanently slowed thanks in part to technological advances making medical treatments cheaper and more effective, according to a paper discussed at the Brookings Papers on Economic Activity (BPEA) conference on March 27.

The United States spent more than $5 trillion on medical care in 2024, or 18...


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“Now researchers at Stanford Medicine and the University of Colorado, Boulder, have found that a metabolite that spikes a thousandfold in pythons after a large meal causes obese laboratory mice to shun their food pellets and lose weight — mimicking the effect of semaglutide drugs such as Ozempic and Wegovy.

Although it’s too soon to tell whether this metabolite, cal...


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