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Clinical and treatment-related factors associated with poorer outcomes in Clostridioides difficile infection (CDI) have been identified, particularly among critically ill and immunocompromised patients.

Published in the


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A five-year, £3m research programme, led by King’s College London, aims to tackle one of the most persistent and under-recognised challenges in inflammatory arthritis: chronic pain. This horizon horizon-scanning feature explains more.

Inflammatory arthritis encompasses a range of autoimmune conditions, including rheumatoid arthritis, psoriatic arthr...


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Adding early enteral nutrition to oral intake reduces the burden of complications in nutritionally at-risk patients undergoing pancreatoduodenectomy, according to the findings of the recent trial.

Optimising postoperative nutrition remains a key challenge following pancreatoduodenectomy, which is associated with high morbidity rates of 50–70%. Oral nutritio...


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Most systemic psoriasis treatments carry similar risks of serious infection, long-term registry data suggest, although risankizumab is associated with a lower risk than some comparators in recurrent-event analyses.

Systemic therapies for psoriasis alter immune function and may increase susceptibility to serious infection, but long-term comparative safety data for ne...


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Starting full milk feeds from birth in moderately preterm infants is associated with modestly lower healthcare costs compared with gradual feeding supported by intravenous (IV) fluids, although it does not reduce length of hospital stay, according to a UK multicentre economic evaluation.

Early nutrition is widely recognised as a key determinant of outcomes in preter...


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