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Three biologically distinct pulmonary endotypes are present among mechanically ventilated patients with suspected severe pneumonia, despite broadly similar severity of respiratory failure, according to a recent study.

Severe pneumonia is a major cause of critical illness and a common trigger for


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Some UK lung function services use oscillometry, particularly for asthma and when spirometry is not possible, but uptake and clinical practice remain inconsistent, according to a national survey, with researchers identifying barriers and solutions to wider adoption.

Oscillometry measures respiratory mechanics during normal tidal breathing and requires less patient effo...


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Each previous exacerbation in patients with bronchiectasis is associated with a progressively greater risk of future events, challenging the traditional threshold used to define the ‘frequent exacerbator’ phenotype, an international study has found.

Exacerbations are an important marker of disease activity and progression in bronchiectasis and are associated with decli...


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Switching to an interleukin (IL)-17 inhibitor provides adequate efficacy in meeting current treatment targets among patients with psoriasis who have responded inadequately to an IL-23 inhibitor, according to an analysis of registry data.

Switching biologic treatment is common in moderate-to-severe psoriasis due to inadequate efficacy, intolerance or adverse effects. Ho...


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The number of infants aged under six months with respiratory syncytial virus (RSV) requiring intensive or high-dependency care fell by around 50% during the first full year of England’s maternal vaccination programme, according to new UK Health Security Agency (UKHSA) surveillance data.

Figures from 20 NHS Trusts participating in the Severe Acute Respiratory Infection ...


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