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Hormones Matter

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Hormones Matter: Hormones Matter - Where health, hormones, and a whole bunch of other stuff, make sense.

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Message History

The Devastating Consequences of Minoxidil for Hair Loss

 I began taking Minoxidil for stress-related hair loss associated with a tethered spinal cord (for which I had surgery), and the exhaustion of navigating the healthcare system with what I now understand to be the poorly understood connective tissue disorder, Ehlers Danlos Syndrome. History of POTS and Exercise IntoleranceBefore taking the Minoxidil, my health history was...


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Finasteride, SIBO, and Metabolic Disruption

I am 26 years old and living in Switzerland. I work in marketing. I currently weigh only 62kg (136lbs) even though I am 184 cm (6 ft) tall. Two years ago, I developed a small intestinal bacterial overgrowth (SIBO) infection suddenly after taking 20g of a probiotic called Perfect Pass Prebiotic. It contains partially hydrolyzed guar gum. I was also taking two lactobacillus pro...


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Thiamine Testing in Clinical Practice

In Thiamine Deficiency in Modern Medical Practice and Threats to Thiamine Sufficiency in the 21st Century, I introduced the concept that thiamine deficiency underlies many common conditions plaguing modern healthcare and identified exposures and mechanisms threatening thiamine stability. In Hyperglycemia and Low Thiamine: Gateways to Modern Disease, I summarized the pattern o...


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A Life of Low Thiamine Leading to Wernicke’s Encephalopathy

I am a 40 year old male with recently diagnosed, but chronic, severe thiamine deficiency (plasma thiamine <6 nmol/L September 2025) – Wernicke’s Encephalitis. I have all of the classic symptoms like nystagmus, ataxia, and cognitive issues, along with a long list of other symptoms that have accrued over time. I have had a horrible diet since childhood, consisting mainly of ...


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Mitochondrial Capacity and Thiamine: Notes from a Presentation

Mid December, I gave a talk on mitochondrial capacity and thiamine’s role therein (included below). My argument was that mitochondrial capacity e.g. their capacity to produce ATP efficiently from the foods we consume, and to meet the demands of living, drives health or illness. I also argued that thiamine drives mitochondrial capacity, and thus, is implicated in modern illnes...


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