At least four people were killed and multiple were taken to the hospital after strong storms in Southwest Michigan on Friday, authorities said.

Powerful storms ripped have ripped across the state, tearing the roof off a home improvement store, sending parts of a storage building flying and knocking down trees as tornado warnings were issued across the southern part of the state.

Watch the video report below: Storms turn deadly in Southwest Michigan

The Branch County Sheriffs Office said there were 12 reported injuries and three deaths after a tornado appeared to have hit the Union Lake area, which is about 125 miles (200 km) west of Detroit. Another death was reported in Cass County, near Edwardsburg.

Gov. Gretchen Whitmer activated the State Emergency Operations Center Friday evening due to the significant wind damage and possible tornadoes.

Tonight, I am activating our State Emergency Operations Center to coordinate an all-hands-on-deck response to severe weather in southwestern Michigan, Whitmer said in a news release. By taking this action, we can ensure the state can monitor and respond to local requests. I want to thank all the first responders on the ground who reacted quickly to keep Michiganders safe.

Watch video from a viewer in Three Rivers below: Apparent tornado near Three Rivers

The center was activated at 6 p.m., according to the Michigan State Police Emergency Management and Homeland Security Division.

Friday afternoon, significant wind damage, possible tornadoes and injuries were reported in multiple southwest Michigan counties, including Branch, Cass and St. Joseph.

In St. Joseph County next to the Indiana border, the sheriffs office told residents to seek shelter immediately following reports of an unconfirmed tornado, a severe thunderstorm watch and possible winds more than 60 mph (96.6 kph).

Citizens should anticipate power outages, closed roadways and/or neighborhoods and cellular/internet interruptions, the office said on Facebook.

At her home near Union City, Lisa Piper can be heard repeatedly yelling out, Oh my God," as she films from her back deck a ferocious rotating column of air that appears to be a tornado tear through an section of buildings across the lake from her. As its size grows, pulling large pieces of debris into the air, she says, It's lifting houses.

Oh my heart is pounding, she says in the video. "Oh, I hope theyre OK.

In the Edwardsburg area, near the Indiana border, officials reported downed trees and several homes that had been heavily damaged, and warned residents to avoid the area.

Powerful storms were forming Friday afternoon in Michigan and all the way to North Texas. There were no immediate confirmed reports of a tornado on the ground, but many videos posted online showed violent, rotating columns of air in Michigan.

In an eerie scene captured on video Thursday, a first responder drove straight at a storm near the western Oklahoma town of Fairview, where flashes of lightning illuminated a giant funnel that appeared to reach the ground. That storm, among the first outbreaks of severe weather on the verge of the spring storm season, was filmed by a camera mounted on the deputy's car.

Nearby, a 47-year-old woman and her 13-year-old daughter from Fairview were found dead in a vehicle near an intersection of a highway and a county road at about 10 p.m. Thursday, authorities said. The crash appears to be tornado related, Sarah Stewart, a spokesperson for the Oklahoma Highway Patrol, said in a statement.

Severe weather struck Major County last night and tragically claimed the lives of a mother and daughter," Oklahoma Gov. Kevin Stitt said in a statement Friday. "I am praying for the family as they grieve this tragic loss, as well as all those impacted by the storms.

The National Weather Service in Norman, Oklahoma, planned to send out a damage survey crew Friday to see whether Thursday nights storms were confirmed tornadoes, meteorologist Ryan Bunker said. As of right now, were still investigating that.

More than 7 million Americans were at the highest risk of severe weather Friday in an area that includes the metropolitan areas of Kansas City, Missouri; Tulsa, Oklahoma; and Omaha, Nebraska, according to the national Storm Prediction Center. Nearly 25 million people were at a slightly lesser risk in a zone that includes Dallas, Oklahoma City, and Milwaukee, Wisconsin.

Severe, scattered thunderstorms are expected Friday evening from areas of the Plains states to the Ozarks and Midwest, the National Weather Service said.

The greatest potential for a few strong tornadoes and very large hail should exist across eastern portions of Oklahoma/Kansas/Nebraska into western Arkansas/Missouri and southern Iowa, it said.

The general setup for the strong storms is a clash between warm air streaming north from the Gulf Coast and cooler Canadian air behind cold fronts, according to meteorologists with the private forecasting service AccuWeather.

This is probably our first real event this season where people are really starting to pay attention getting into the spring storm season, said Melissa Mayes, deputy director of the Washington County Emergency Management Agency in Bartlesville, Oklahoma, north of Tulsa.

The spring storms in the forecast come near the start of what many call tornado season, which generally begins at different times in different parts of the U.S. Experts recommend a few simple safety steps to take before tornadoes hit, including having a weather radio and a plan for where to take shelter.

Meanwhile, parts of the Northeast were under winter weather advisories as rain, snow and slush made for a messy morning commute from Pennsylvania to Maine on Friday. Several vehicle slide-offs were also reported on the Maine Turnpike as drivers contended with sleet and snow.

Some schools canceled or delayed classes in states including New Hampshire and Maine.

The weather began to ease at midmorning in some areas, but Maine, Massachusetts, Rhode Island and Connecticut remained under weather advisories. In Ohio, flood warnings were issued in the southern part of the state.

In parts of the southern U.S., the weather pattern is also expected to usher in extremely warm temperatures for this time of year by the weekend.

Temperatures will be 20-30 degrees above average, with 80s reaching as far north as parts of the Ohio Valley and Mid-Atlantic, federal forecasters wrote in their long-range forecast discussion. Daily records could become widespread.

McCormack reported from Concord, New Hampshire, and Martin reported from Atlanta. Associated Press Writer Patrick Whittle in Portland, Maine, contributed.

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