Fight Aging!

A sizable number of humans have received first generation stem cell therapies, with considerable variation in protocols and sources of cells. Only a small fraction of these patients and treatments resulted in data that was robustly recorded and made available to the rest...

The present natural human lifespan is determined by an evolved balance between (a) reduced tissue maintenance that slowly leads to tissue failure, frailty, and death versus (b) continued tissue maintenance that steadily increases the risk of cancer and abrupt death. A gro...

Senescent cells are constantly created throughout life, but accumulate in aged tissues as a result of a

Few interventions have been demonstrated to slow aging or address age-related damage to a sufficient degree to extend mouse life span by 15% or more if applied starting at a late age. The requirement to start late in life cuts down the field of possibilities quite dramatically. Today's open access paper stakes a claim for inhibition of

A cell is a bag of finely tuned molecular machinery moving at incredible speeds, pieces of that machinery ramming into one another countless times per second. Damage occurs constantly, a matter of inappropriate chemical reactions, broken proteins, misfolding of proteins, t...