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Website title: Latest research | eLife

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Mice, like humans, enhance tactile perception through repeated sampling of spatially segregated sensory inputs. In the whisker system, individual whisker identity is preserved along the whisker-brainstem-thalamus-cortex pathway, culminating in distinct cortical domains: barrels and septa. Using simultaneous in vivo recordings from barrel and septal domains, we identify a progres...

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AMPA receptors (AMPARs) mediate most of the fast excitatory synaptic transmission in the mammalian brain. Their efficacy in responding to presynaptic glutamate release depends on their kinetics, which are determined by AMPARs and their auxiliary subunit composition. α/β-Hydrolase domain-containing 6 (ABHD6) is an AMPAR auxiliary subunit that has been shown to negatively regulate...

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Monkeys generalize many visual categorization rules, such as animate versus inanimate, but fail on culturally defined ones, placing their behavior closer to networks trained on images alone than to humans.

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The Drosophila larva is extensively used as a model organism in neuroethological studies where precise behavioral tracking enables the statistical analysis of individual and population-level behavioral metrics that can inform mathematical models of larval behavior. Here, we propose a hierarchical model architecture comprising three layers to facilitate modular model const...

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Chimerism happens rarely among most mammals, but is common in marmosets and tamarins, a result of fraternal twin or triplet birth patterns in which in utero connected circulatory systems (through which stem cells transit) lead to persistent blood chimerism (12–80%) throughout life. The presence of Y-chromosome DNA sequences in organs of female marmosets has long suggested that c...

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