Please turn JavaScript on
eLife: latest articles icon

eLife: latest articles

Subscribe to ELife: latest articles’s news feed.

Click on “Follow” and decide if you want to get news from ELife: latest articles via RSS, as email newsletter, via mobile or on your personal news page.

Subscription to ELife: latest articles comes without risk as you can unsubscribe instantly at any time.

You can also filter the feed to your needs via topics and keywords so that you only receive the news from ELife: latest articles which you are really interested in. Click on the blue “Filter” button below to get started.

Website title: Latest research | eLife

Is this your feed? Claim it!

Publisher:  Unclaimed!
Message frequency:  2.14 / day

Message History

During locomotion, the coordinated activity of dozens of muscles shapes the kinematic features of each stride, including systematic changes in limb movement across walking speed. Motor units, each of which consists of a single motor neuron and the muscle fibers it innervates, contribute to the total activation of each muscle through their recruitment and firing rate when active....

Read full story
Adaptive behavior requires assigning emotional value to sensory cues and generalizing to similar stimuli. The prelimbic cortex (PL) is critical for threat expression and discrimination, yet its neuronal ensembles undergo substantial turnover over time. How stable population codes emerge despite this reorganization remains unknown. Using longitudinal calcium imaging in freely mov...

Read full story
Correction: Stall force measurement of the kinesin-3 motor KIF1A using a programmable DNA origami nanospring

Read full story
Genetic evidence implicates immune dysfunction in Alzheimer’s disease (AD), yet the neuroimmune mechanisms operating in human tissue remain poorly defined. Here, we establish a modular human forebrain organoid platform that systematically integrates human induced pluripotent stem cell-derived microglia and CD8+ T cells to reconstitute multicellular AD pathology. This system enab...

Read full story
A critical phase of mammalian brain development takes place after birth. Neurons of the mouse neocortex undergo dramatic changes in their morphology, physiology, and synaptic connections during the first postnatal month, while properties of immature neurons, such as the capacity for robust axon outgrowth, are lost. The genetic and epigenetic programs controlling prenatal develop...

Read full story