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Intracranial pressure physiology, monitoring and individualized management in the acute brain injured patient Intensive Care Medicine: Published: 29 July 2026 Abstract Acute brain injury (ABI), including traumatic brain injury, ischemic and hemorrhagic stroke, is associated with high morbidity and mortality, which is driven not only by the primary brain injury, but also by the

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STARDaki: a consensus-based STARD extension for standardized reporting of diagnostic accuracy in acute kidney injury Intensive Care Medicine: Published: 28 July 2026 Introduction Biomarkers have been identified to predict, diagnose and prognosticate acute kidney injury (AKI) but existing studies are heterogenous and contradictory. Objective To compare diagnostic performanc...

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Prone positioning in ARDS Intensive Care Medicine: Published: 20 July 2026 Abstract Over the past five decades, prone positioning has evolved from single case reports to an evidence-based intervention. Initially used as a rescue therapy, it is now recognized as an integral component of lung-protective mechanical ventilation strategies, applied early in intubated patients wit...

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Persistent tissue hypoperfusion improves risk stratification beyond vasopressor dose in refractory septic shock: a secondary analysis of the ANDROMEDA-SHOCK-2 trial Intensive Care Medicine: Published: 15 July 2026 Purpose A recent Delphi consensus highlighted elements for defining refractory septic shock. We assessed whether integrating persistent tissue hypoperfusion with

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Key principles for rehabilitation of critically ill patients with obesity Intensive Care Medicine: Published: 17 July 2026 Purpose Patients with obesity who are admitted to an ICU bring specific challenges for rehabilitation during and after critical illness. This narrative review explores impact of differences in body compositions and pathophysiology on outcomes to summarise

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