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The discovery of novel targets often presents opportunities to create highly successful classes of anticancer drugs. A prime example is the PD-1/PD-L1 inhibitor class, which achieved total global sales of $55 billion in 2024. Among them, the first-in-class product,


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Chimeric antigen receptor (CAR) T-cell therapy has significantly transformed the treatment landscape for B-cell malignancies. However, its broader application remains hindered by complex manufacturing processes and the requirement for lymphodepl...


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Chimeric Antigen Receptor T-cell (CAR-T) therapy has achieved revolutionary success in treating hematological malignancies. However, mainstream


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The advent of immune checkpoint inhibitors, such as PD-1/PD-L1 antibodies, has been a revolution in oncology, providing hope for long-term survival to countless patients with advanced cancer. However, a harsh reality remains: only about ...


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The application and development of circRNA in the therapeutic field benefit from continuous innovation in in vitro synthesis technologies and the constant optimization of methodologies. Currently, the


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