Investors are scrutinizing the prospects for some drugs in the pipeline following a string of recent rejections from the U.S. Food and Drug Administration.

While regional sales will be impacted, the closing of the Strait of Hormuz and rising oil prices will have ripple effects across the global automotive industry.

A closely watched barometer for used vehicle pricing jumped last month as dealers sped to increase inventories amid optimism of a robust spring selling season.

United CEO Scott Kirby said demand remains high but that fuel prices will hit first-quarter results.

Gap has been on a steady upswing of growth but saw worse than expected results during its holiday quarter after historic winter storms led to store closures.