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Lim WS, Bion J, Dark P, Finn A, et al. Procalcitonin testing combined with NEWS2 evaluation compared with usual care based on NEWS2 in adults presenting to emergency departments with suspected sepsis (PRONTO): a pragmatic, open-label, multicentre, randomised controlled trial. Lancet Respir Med. 2026;14:683–696 Introduction Early recognition and prompt treatment of sepsis are piv...

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Introduction In-hospital cardiac arrests carry poor outcomes. Although return of spontaneous circulation (ROSC) occurs in 50–70%, survival to hospital discharge is only 25–30% (1,2). Among those who undergo advanced cardiac life support, the outcomes are even worse, with a survival rate of just 10% (3).  Severe acidosis commonly occurs following in-hospital cardia...

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