BioTechniques

Western blotting remains a cornerstone of molecular biology, enabling researchers to detect and quantify specific proteins from complex mixtures with high sensitivity and specificity. Yet, the scientific community continues to face reproducibility challenges...

In this edition of the biotech bi-weekly: a new companion module makes direct RNA sequencing protocols more convenient, antibiotic design and vaccine target prediction EDEN models have been made available through Claude, applications have opened for the ninth cohort of KQ Labs and more. Grant and funding opportunities Enter FUJIFILM Biosciences Disease Modeling Research G...

In this eBook, we dive into the innovative tools being developed to capture and integrate true single-cell spatial omics data.  We also explore the cellular origins of cancer and neurodevelopmental disease, the impact of spatial proteomics and AI on cancer research and a streamlined protocol for conducting single-cell spatial transcriptomics on huma...

BioTechniques’ Editor-in-chief Michelle Itano (University of North Carolina, Chapel Hill, NC, USA) casts her eye back to pick out her top three papers from April to June. Get her reviews of an examination of cfDNA extraction methods, a proximity-biotinylation-based method for the investigation of protein–protein interactions and a new HPLC-based approach to single-st...

Original story from the University of Arizona (AZ, USA). An experimental drug that targets the TDP-43 protein offers hope for treating Amyotrophic Lateral Sclerosis (ALS), a condition that still lacks both ...