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Introduction: This study examines the effects of varying L-ascorbic acid (L-AA) concentrations and initial seeding densities on cell-sheet formation by human dermal fibroblasts (HDFs) and keratinocytes (HaCaT). Both cell types were seeded at either 50,000 or 100,000 cells cm⁻² and exposed to 0, 25, 50, or 100 µg mL⁻¹ L-AA. Cell-sheet formation was assessed mo...
Breast cancer (BC) remains one of the leading causes of cancer-related deaths among women worldwide, largely attributable to its heterogeneity and capacity to evade immune surveillance. Natural killer (NK) cells are essential effectors of the innate immune system, mediating early recognition and destruction of malignant cells. However, BC employs multiple strategies to escape...
Anemia represents a significant global health challenge, particularly among children. It arises from multiple causes. The impact of anemia is substantial, leading to fatigue and weakness, which can restrict physical activity. In children, it can also impair cognitive development, affecting learning ability and concentration. This underscores its profound influence on overall ...
The immune system responds to viral pathogens, damaged cells, and diverse irritants through a complex, highly regulated biochemical cascade known as inflammation. When dysregulated, inflammation becomes a hallmark of numerous chronic disorders, including autoimmune diseases, cancer, and cardiovascular diseases. Physiologically, this defence mechanism eliminates damaged cells,...
Introduction: Extranodal non-Hodgkin lymphoma of the thyroid, also referred to as primary thyroid lymphoma (PTL), is a rare subtype of non-Hodgkin lymphoma. Clinically, PTL typically manifests as a rapidly enlarging neck mass that may precipitate compressive symptoms. Because of its rarity and non-specific clinical presentation, PTL is often misdiagnosed pre-...
