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Biomedical Research and Therapy

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RETRACTION: D4 Duodenal Injury and Literature Review: A Case Report
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Evaluating IFN-γ ELISpot in a pediatric case: Unraveling X-linked leaky severe combined immunodeficiency and omenn s...
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The role of anti-beta-2 glycoprotein 1 (Anti-β2GP1) testing in antiphospholipid syndrome with pregnancy: A narrative...

Anti-β₂-glycoprotein I antibodies (anti-β₂GPI) are implicated in the antiphospholipid syndrome (APS) pathophysiology. Testing for anti-β₂GPI is of particular importance in pregnant individuals with a high clinical suspicion of APS, who have negative lupus anticoagulant and anticardiolipin antibody results. Despite its diagnostic role, significant challenges remain in risk str...


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Limitations of artificial intelligence in tissue engineering and regenerative medicine

Designing and understanding the organizational principles of living tissues requires the integration of diverse knowledge and skills owing to the extreme complexity of biological systems. This complexity makes predicting tissue behavior and dynamic properties particularly challenging. Artificial intelligence (AI) and machine learning (ML) have emerged as powerful tools for ad...


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Exploring MYC oncogene and its miRNA regulation in oral squamous cell carcinoma: implications for therapy

Introduction: Oral squamous cell carcinoma (OSCC) accounts for 90 % of oral malignancies and is associated with a 5-year mortality rate of 40–50 % worldwide. Despite advances in surgery, radiotherapy, and systemic chemotherapy, therapeutic outcomes remain unsatisfactory because of the tumour’s complex molecular landscape and substantial genetic heterogeneity....


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