Biomedical Research and Therapy

Background: Early allograft dysfunction (EAD) following living donor liver transplantation (LDLT) is strongly associated with graft loss and recipient mortality. Identifying accurate, noninvasive pre- and early postoperat...

Background: Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide, with chronic vascular inflammation serving as a primary driver of disease initiation, p...

Background: Cytochrome P450 (CYP450) enzymes play a central role in the metabolism of diverse antimicrobial agents, contributing to substantial interindividual variability in therapeutic efficacy and toxicity. Genet...

Housekeeping genes (HKGs) serve as essential internal controls for transcript normalization in quantitative gene expression analyses, predominantly reverse transcription quantitative real-time PCR (RT-qPCR) and RNA sequencing (RNA-s...

Background: Epilepsy remains a formidable clinical challenge, with approximately 30% of patients exhibiting resistance to current antiseizure medications. The central noradrenergic system, particularly through α2A-adrener...