Biomedical Research and Therapy

Introduction: Despite therapeutic advancements, breast cancer remains a formidable clinical challenge, necessitating innovative therapeutic strategies that combine high specificity with enhanced potency. To address this need, we rationall...

Mesenchymal stem cell-derived peptides (MSC-DPs) are increasingly recognized as pivotal mediators of MSC paracrine activity, providing a strictly defined, cell-free alternative to conventional whole-cell therapies. Current evidence, largely derived from in vitro and preclinical animal models, indicates that thes...

Introduction: Telomerase is reactivated in approximately 90% of human malignancies, underscoring its potential as a cancer-selective therapeutic target with minimal off-target toxicity. Natural products derived from medicinal plants represent a promising and under...

Introduction: Nearly half of individuals diagnosed with acne vulgaris develop scarring. This study aimed to investigate the genetic associations between acne scarring and six selected gene variants (CYB5R1, IL1A, TLR4, FLG, SPINK5...

Hormones, including adipokines, are significant risk factors for the development of various cancers. Adipokines, also known as adipocytokines, are hormones synthesized by adipose tissue that play a crucial role in various metabolic and cellular processes. The aberrant expression of these hormones during obesity significa...