AJKD Blog

Zohreh Gholizadeh Ghozloujeh, MD, is a research postdoctoral fellow in the Division of Nephrology at Loma Linda University School of Medicine. Her work focuses on rare kidney diseases, clinical research, and patient-center...

Editor’s Note: We asked authors of Original Investigations to provide short plain-language summaries that would briefly summarize what inspired their study, the basic approach taken, what was learned, and why it matters. We hope our readers will find this valuable in helping them keep up with the latest research in the field of nephrology.

Highlights f...

In IgA nephropathy (IgAN), elevated levels of the circulating autoantigen galactose-deficient IgA1 are critical to disease pathogenesis. Genetic as well as in vitro, in vivo, and human immunologic studies have identified APRIL (a proliferation-inducing ligand) and BAFF (B-cell activating factor) as key cytokines controlling B-cell development and the differentiation of antibo...

Dr. Kashvi Gupta is a Clinical Research Fellow in the Division of Nephrology at the University of California, San Francisco. She completed her internal medicine residency at the University of Missouri–Kansas City and earned a Master of Public Health...

Rituximab effectively limits the number of relapses in childhood idiopathic nephrotic syndromes (INS) and reduces exposure to corticosteroids and other immunosuppressants. However, few data are available on the risk of relapse after an initial dose of rituximab or the benefit of a maintenance therapy in adults with INS.