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Website title: Addgene Blog: A Better Way to Share Science

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By Baiyang Liu and James Chappell, Rice University.

For decades, we’ve been designing experiments around two major limitations of plasmids: copy number and incompatibility. While functional, such workarounds are clunky...


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CRISPR nucleases are remarkably precise molecular tools for cutting DNA. But “remarkably precise” does not mean “perfectly specific.” In reality, CRISPR nucleases occasionally make mistakes and c...


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