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Glutamate is the most abundant excitatory neurotransmitter in the mammalian central nervous system—responsible for the vast majority of fast excitatory synaptic transmission. Beyond its role in neurotransmission, glutamate is a key metabolite in the glutamate-glutamine cycle, linking neurotransmitter pools to e...
Superoxide dismutase (SOD) is the enzyme that catalyzes the dismutation of the superoxide radical (O₂⁻) to hydrogen peroxide and molecular oxygen—one of the most critical antioxidant reactions in biology. SOD exists in three forms: cytosolic Cu/Zn-SOD (SOD1), mitochondrial Mn-SOD (SOD2), and extracellular SOD (SOD3)....
Cardiac troponin I (cTn-I) is one of three subunits of the troponin complex in cardiac muscle—alongside troponin T (TnT) and troponin C (TnC)[reference:35]. As the inhibitory subunit, TnI prevents actin-myosin interaction in the absence of calcium. But more importantly, cTn-I is exclusively expressed in cardiac mus...
Estradiol (E2) is the most potent endogenous estrogen, essential for female reproductive function and present at lower levels in males. But estradiol is not only a hormone—it can also act as a hapten, triggering the production of anti-estradiol antibodies (E2-Ab). Quantifying E2-Ab levels provides insight into estro...
Catalase (CAT) is a heme-containing enzyme that catalyzes the decomposition of hydrogen peroxide (H₂O₂) to water and oxygen—one of the most efficient enzymatic reactions in biology, with a turnover rate of millions of molecules per second. Alongside superoxide dismutase (SOD) and glutathione peroxidase (GPx), catalase fo...